Hello to new readers huntster, lasvegaslynn, and primal_pastry!
Exhaustion, nausea, full-body pain. Just took brain drugs.
Your Daily Science
"Thirst for Knowledge" may be Opium Craving
Neuroscientists have proposed a simple explanation for the pleasure of grasping a new concept: The brain is getting its fix. The "click" of comprehension triggers a biochemical cascade that rewards the brain with a shot of natural opium-like substances, said Irving Biederman of the University of Southern California. He presents his theory in an invited article in the latest issue of American Scientist.
"While you're trying to understand a difficult theorem, it's not fun," said Biederman, professor of neuroscience in the USC College of Letters, Arts and Sciences.
"But once you get it, you just feel fabulous."
The brain's craving for a fix motivates humans to maximize the rate at which they absorb knowledge, he said.
"I think we're exquisitely tuned to this as if we're junkies, second by second."
Biederman hypothesized that knowledge addiction has strong evolutionary value because mate selection correlates closely with perceived intelligence.
Only more pressing material needs, such as hunger, can suspend the quest for knowledge, he added.
The same mechanism is involved in the aesthetic experience, Biederman said, providing a neurological explanation for the pleasure we derive from art.
"This account may provide a plausible and very simple mechanism for aesthetic and perceptual and cognitive curiosity."
Biederman's theory was inspired by a widely ignored 25-year-old finding that mu-opioid receptors – binding sites for natural opiates – increase in density along the ventral visual pathway, a part of the brain involved in image recognition and processing.
The receptors are tightly packed in the areas of the pathway linked to comprehension and interpretation of images, but sparse in areas where visual stimuli first hit the cortex.
Biederman's theory holds that the greater the neural activity in the areas rich in opioid receptors, the greater the pleasure.
In a series of functional magnetic resonance imaging trials with human volunteers exposed to a wide variety of images, Biederman's research group found that strongly preferred images prompted the greatest fMRI activity in more complex areas of the ventral visual pathway. (The data from the studies are being submitted for publication.)
Biederman also found that repeated viewing of an attractive image lessened both the rating of pleasure and the activity in the opioid-rich areas. In his article, he explains this familiar experience with a neural-network model termed "competitive learning."
In competitive learning (also known as "Neural Darwinism"), the first presentation of an image activates many neurons, some strongly and a greater number only weakly.
With repetition of the image, the connections to the strongly activated neurons grow in strength. But the strongly activated neurons inhibit their weakly activated neighbors, causing a net reduction in activity. This reduction in activity, Biederman's research shows, parallels the decline in the pleasure felt during repeated viewing.
"One advantage of competitive learning is that the inhibited neurons are now free to code for other stimulus patterns," Biederman writes.
This preference for novel concepts also has evolutionary value, he added.
"The system is essentially designed to maximize the rate at which you acquire new but interpretable [understandable] information. Once you have acquired the information, you best spend your time learning something else.
"There's this incredible selectivity that we show in real time. Without thinking about it, we pick out experiences that are richly interpretable but novel."
The theory, while currently tested only in the visual system, likely applies to other senses, Biederman said.
Your Daily BPAL
I was only supposed to do BPAL after I did writing, but I am cheating, because I do not feel well, so there. I promise to write after my nap. If I can manage to nap.
Dorian:This blend is an artful deception: a sweet gilded blossom lying over a twisted and corrupted core. A Victorian fougere with three pale musks and dark, sugared vanilla tea.
I actually tried Dorian on Saturday, but found myself utterly unable to smell it. Perhaps this was due to brainfry. Let's try it again.
In the bottle: Sweet. I smell that sugared vanilla.
On me: Ditto on the sweet, with the tea pushing through. BPAL tea likes me. This is a different sweet-tea from White Rabbit's tea-and-honey, though. This is overly sweet. Maybe it's the vanilla that nudges it. ...And yep, the vanilla has taken over. And I'm really not getting any musk off this. Poo. :(
...but wait; it has mellowed! Hm. We shall see.
Three Witches: Warm cinnamon, husky clove and white pepper.
In the bottle: Wooooyeah clove!
On me: Wooooyeah clove! And cinnamon. The pepper is barely making an appearance. Fortunately, the cinnamon is staying cinnamon-bark and not heading toward red-hots territory. Okay. This is nice. A little less nuanced than most of their stuff, but nice.
...wait. Aii. Red-hots. Not as strong as Wrath, though. I shall wait and see if it passes.
Ack. It burns! No, seriously. It's burning my skin. I do not know why, as all three of these ingredients are fine in other scents.
Lightning: The electric tang of ozone, marine notes, and a drop of sharp rain.
In the bottle: Yep, ozone.
On me: Chemical eww. Dammit. *sigh* gegenschein and I pretty well confirmed on Tuesday that BPAL's aquatic notes Do Not work on me.
Re-smell: But wait. Now is watery without chemical eww. Okay, we shall wait and see.
Debauchery: A sinful, licentious scent: self-indulgent and luxurious. Mingled heady civet and red Egyptian musk, thickened with opium.
Well, I guess if civet's a problem, I'm about to find out.
In the bottle: Erf. Just *weird*.
On me: Still weird. Definite animal-musk.
...and... my skin is eating it. Wow, that went faint fast. :( Oh, wait! It's coming back...
The brain-meds have hit. I think maybe I can sleep now.